Baltimore Orioles at San Francisco Giants odds, picks and predictions

The Baltimore Orioles (36-21) and San Francisco Giants (28-29) meet Saturday for game 2 of a 3-game series. First pitch from Oracle Park is set for 10:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 1-0

Baltimore won 3-2 as +142 underdogs in Friday’s series opener behind DH Gunnar Henderson’s go-ahead, 7th-inning solo homer. The Orioles have alternated wins and losses in their last 6 games, going 3-3.

The Giants have now dropped 3 in a row after winning the home opener of a current 6-game stand. They are still above .500 at home (16-14). However, the Orioles own a dominant 19-9 road record this season.

Orioles at Giants projected starters

RHP Kyle Bradish vs. RHP Alex Cobb

Bradish (2-1, 3.89 ERA) makes his 10th start of 2023. He has a 1.30 WHIP, 2.9 BB/9 and 7.4 K/9 through 44 IP.

• Last outing: No-decision, 6 2/3 IP, 1 ER, 4 H, 1 BB, 4 K in a 3-2 home win Sunday vs. Texas Rangers
• First career start vs. San Francisco

Cobb (4-2, 3.05 ERA) makes his 12th start. He has a 1.40 WHIP, 2.6 BB/9 and 8.3 K/9 through 62 IP.

• Last outing: Loss, 4 IP, 7 ER, 7 H, 4 BB, 5 K in a 7-5 setback Sunday at Milwaukee Brewers
• Career vs. Baltimore: 7-2, 2.56 ERA (81 IP, 23 ER), 6 HR, 1.15 WHIP, 8.1 K/9 across 13 starts

Orioles at Giants odds

BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:39 a.m. ET.

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Orioles at Giants picks and predictions

Prediction

Orioles 5, Giants 4

BET ORIOLES (+110).

Baltimore’s dominance on the road makes it the much safer bet. The underdog is 5-5 in the Orioles’ last 10 meetings overall, with Baltimore winning as the underdog in 3 of those 5 games (per TeamRankings.com).

Meanwhile, the Giants are 0-8 in their last 8 interleague home games vs. a right-handed starter, according to Covers.com.

PASS.

The line is simply not worth the juice for either side, bet on the moneyline and/or O/U total for this game.

Plus, we’re already invested in the Baltimore ML.

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LEAN OVER 8 (-110).

The Over is 4-0-1 in Bradish’s last 5 starts with 5 days of rest and 5-0 in Baltimore’s last 5 games vs. a starter with a WHIP of less than 1.15.

Both teams are each 5-5 O/U in their last 10 games overall.

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