Michigan vs. Illinois prediction, odds, line: 2022 Week 12 college football picks, best bets by proven model

Summarized by: Live Sports Direct
 

Illinois Fighting Illini are 7-3 and 4-2 in the Big Ten, while Michigan is 10-0 and 7'0. The Wolverines are 17.5-point favorites against Illinois. Michigan takes on Ohio State next week. SportsLine's advanced computer model simulates every college football game 10,000 times. It has returned a profit of almost $3,100 for $100 players on its top-rated college picks against the spread.

Michigan leads the country in scoring defense (11.2 points per game) and rushing yards per play (144. 2). Michigan is favored by 17.5 points. Illinois is a 2nd-ranked rushing team (143.6 yards).

Michigan leads the country in scoring defense (11.2 points per game) and second in the nation in rushing yards per games (144. 2). Michigan vs. Illinois money line is Wolverines -800, Illini +550.

Blake Corum is one of the most productive running backs in the country. Michigan is fourth in rushing yards per game and one the least penalized teams in FBS. Illinois is 119th in penalty yards.

Illinois has one of the best defensive backs in the country in Devon Witherspoon. The Illini lead the nation in interceptions (17), passing efficiency defense (90.37) and forced incompletions (14). Johnny Newton and Keith Randolph Jr. have combined for 68 pressures this season.

SportsLine's model is leaning Over on the total. It projects a combined 48 points for Michigan and Illinois. One side of the spread hits in well over 50% of simulations.


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