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Seahawks at 49ers spread, odds, picks: Expert predictions for Week 2 matchup

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Seahawks at 49ers spread, odds, picks: Expert predictions for Week 2 matchup

The Seattle Seahawks and San Francisco 49ers are playing each other in the NFC West on Sunday at 4:05 p.m. ET at Levi’s Stadium in Santa Clara. Seattle won the first game in Seattle, while San Fran lost to Chicago. The 49er offense had a rough game against Chicago, but they are still comfortable favorites.

Seahawks are favored to beat the 49ers in the Week 2 game.

Seahawks are without Joey Blount and Justin Coleman. Artie Burns is injured.

Seahawks are without Daniel Brunskill and George Kittle.

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George Kittle
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