Pittsburgh Pirates at San Diego Padres odds, picks and predictions

"}" data-sheets-userformat="{"2":14851,"3":{"1":0},"4":{"1":2,"2":16777215},"12":0,"14":{"1":2,"2":0},"15":"Calibri, sans-serif","16":11}">

The Pittsburgh Pirates (43-56) open a 3-game road series against the San Diego Padres (48-52) Monday. First pitch from PETCO Park is at 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Pirates vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Pirates lead 3-0

The Pirates are coming off a 7-5 road loss to the Los Angeles Angels Sunday. They lost 2 out of 3 games in that series. They are 2-6 since the All-Star break and are in last place in the NL Central.

The Padres return home for the first time since the All-Star break. They went 4-6 on the road trip. They are coming off a 3-1 loss to the Detroit Tigers but took 2 out of 3 games. They are in 4th place in the NL West, 10 games behind the division-leading Los Angeles Dodgers.

Pirates at Padres projected starters

RHP Quinn Priester vs. RHP Yu Darvish

Priester (0-1, 11.81 ERA) makes his 2nd start of his career. He has a 1.69 WHIP, 2 BB and 2 K through 5 1/3 IP.

• Made major league debut last Monday: Loss, 5 1/3 IP, 7 ER, 7 H, 2 BB, 2 K in 11-0 home loss to Cleveland Guardians
• Went 7-3 with 4.31 ERA in 18 starts for AAA Indianapolis

Darvish (7-6, 4.36 ERA) makes his 18th start. He has a 1.26 WHIP, 3.1 BB/9 and 9.7 K/9 through 97 IP.

• Last start: Win, 6 IP, 0 R, 4 H, 3 BB, 7 K in 2-0 road win over Toronto Blue Jays Wednesday
• Has allowed only 1 R in 12 IP (2 starts) since All-Star break

Pirates at Padres odds

BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:40 a.m. ET.

Win your fantasy baseball league with BaseballHQ.com. For decades, BHQ has been helping players just like you win! Use the couple code SBW23 for $15 OFF a Draft Prep or full-season subscription. New customer offer; expires 4/30/2023. Subscribe today and start winning!

Pirates at Padres picks and predictions

Prediction

Padres 7, Pirates 4

The Pirates are 20-30 on the road this season and 3-7 in their last 10 games on the road.

The Padres are 25-23 at home this season and have won 5 of their last 6 games at Petco Park.

Darvish has been dialed in since the All-Star break, allowing only 1 run in his last 12 innings, while Priester allowed 7 runs in his MLB debut last week.

The Padres should win, but at -275 odds, PASS.

The Pirates are 45-54 ATS this season, the 5th-worst mark in the majors, while the Padres are a little better at 49-51 ATS overall.

The Padres are 21-25 ATS at home. The Pirates are 25-25 ATS on the road.

The Pirates’ last 7 losses and 14 of their last 15 have been by more than 1 run.

Twelve of the Padres’ last 12 wins have been by 2 or more runs.

BET PADRES -1.5 (-125). 

Play our free daily Pick’em Challenge and win! Play now!

Six of the Pirates’ last 7 games have had at least 9 total runs.

Seven of the Padres’ last 10 games have had totals of 9 or more runs.

BET OVER 8.5 (-105),

Additional MLB coverage:
BaseballHQ Fantasy Baseball
BaseballPress.com: Your source for every MLB lineup