Week 18 NFL picks, odds, 2023 best bets from proven model: This five-way football parlay pays 25-1

Jacksonville Jaguars host the Tennessee Titans on Saturday. The AFC South title is on the line. Tennessee will start Joshua Dobbs at quarterback, while the Jaguars have won four straight games. They beat the Titans 36-22 on Dec. 11. Jaguars are 6.5-point favorites in the latest Week 18 odds at Caesars Sportsbook. SportsLine's computer model simulates every NFL game 10,000 times and is up well over $7,00 for $100 players on top-rated NFL picks since its inception.

The model simulates every game 10,000 times and it's picking Seattle Seahawks to cover the spread against the Los Angeles Rams. Seattle needs to beat the Lions and win against Rams to have any chance of a wild card slot. The model is picking the Seahawks in more than 50% of simulations.

The model has a five-way football parlay with a payout of 25-1. It also has bets that are off the line for four other NFL games.