Thursday Night Football odds, spread, line: Colts vs. Broncos predictions, NFL picks from expert who's 36-24

Colts vs. Broncos is a Thursday Night Football game on 2022 NFL season. The game starts at 8:15 p.m. ET in Denver. Denver is 3-point home favorite. Colts are 1-2-1 this season after a 24-17 loss to the Tennessee Titans. SportsLine's resident Colts expert, R.J. White, is an expert who's been very successful against the spread and against expectations.

Colts vs. Broncos is Thursday Night Football. Colts are 11-10 against the spread in their last 21 games. Denver is 9-12 against-the-spread in its last21 games, including 9.12 in last three weeks.

Colts vs. Broncos is a game with a spread of 3 points. The over/under is 42.5 points, with Colts money line at -178 and Broncos money +150. Colts are 11-10 against the spread in their last 21 games. Denver is 9-12 against-the-spread in its last21 games, and they are 9th in the last 20.

Colts are in the top ten of the NFL in passing offense, averaging 252 yards per game. They are also above-average in first downs and third down efficiency. On defense, they are No. 6 in run defense and No., 21st in scoring defense.

The Broncos are No. 5 in scoring defense, allowing only 17.0 points per game. Denver has allowed only 19 points in two home games. Patrick Surtain Jr. is one of the best cornerbacks in the NFL. Bradley Chubb has three sacks in first four games for Denver. Indianapolis has not exceeded 20 points this season.

Colts vs. Broncos is a Thursday Night Football game. SportsLine's Mike White is an expert who is 36-24. He's leaning Under.