Clemson vs. Notre Dame preview, prediction: Who wins, and why?

Clemson and Notre Dame are playing in the House that Rockne Built on Saturday. Clemson is in College Football Playoff contention and is ranked No. 4 in CFP rankings. Notre Notre has been playing better lately and has defeated two ACC teams in North Carolina and Syracuse.

Clemson and Notre Dame meet in a football game.

Clemson is 3.5 points behind Notre Dame in the betting line. The over/under for the game is 44.

Football Power Index projects Clemson has 64.8 percent chance to beat the Fighting Irish. The computer has a 35.2 percent shot to upset the visiting Tigers.

Will Shipley has been one of the top rushers in the nation this season. Clemson's main threat is Shiply, who has 739 yards and 10 touchdowns. The Irish are fierce against the run, especially up front. They allow just 129 yards per game and keep opponents to under 4 ypc.

The defensive line of Clemson has been shaky recently. The offensive line could present an opportunity for Notre Dame. Notre Notre has gone over 200 yards rushing in four of its last five games. Audric Estime has 8 of the team's 14 rushing TDs.

Clemson is one of the best teams in college football when it gets in scoring position. Notre Dame is only one team that allows opponents to score 100 percent of time in the red zone.

Clemson has won 14 straight games. Notre Dame is 30-1 in regular season against ACC teams since 2017. Irish have won 5 blocked punts, 1st nationally. Clemson has made the national championship game in 4 of the last 5 seasons when it started 8-0.

Notre Dame will try to get some momentum by running the ball and getting the backs involved in the passing game. DJ Uiagalelei has enough targets to spread the Irish back defense out of position. Clemson has the edge at quarterback, at running back and especially on the defensive front alignment.