Clemson football: Odds, Lines for Tigers vs. Notre Dame
![Clemson football: Odds, Lines for Tigers vs. Notre Dame](/img/li/clemson-football-odds-lines-for-tigers-vs-notre-dame-1.jpg)
Clemson is the betting favorite for their game against Notre Dame. DJ Uiagalelei will start for the Tigers at quarterback. The Tigers are starting the 2022 college football season 8-0 (6-1 ACC). Notre Notre is starting their season at 8.5 (5-2 ACC)